This document is for owners of the Heart Spark Logging Beta who want to know all the nitty gritty details of how the device works. Heart Spark Battery Life Testing shows that battery life is now about 24 hours of data capture and logging. However, battery life is substantially influenced by mode, some flashing modes consume more energy, while others require more current draw. Coin cells are not designed for rapid depletion, they are designed for incredible small loads spread over years think of your typical watch. And again resting it will typically get an hour or two more again. Another issue to consider is temperature. I did some testing, and the caps provide about 1 minute of operating power for the RTC, and about 20 minutes of holding power.
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The Heart Spark is open source and Eric has kindly made the schematics, code, plus lots of other information available on the Sensebridge. To create the Flutter module, firstly I experimented with various combinations of components: an IR proximity sensor, resistor, potentiometer, LED and transistor on a breadboard. The 3.
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In the early years of the Subtle Technologies Festival we put out a general call to artists and scientists and built the program around the themes that emerged. We heard about how virtual worlds emerge as a place where both artists and scientists are engaged in new work. We learned about some dynamic ways that dance can be used as a rich tapestry for expressing scientific ideas.
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Calcium sparks in cardiac myocytes are brief, localized calcium releases from the sarcoplasmic reticulum SR believed to be caused by locally regenerative calcium-induced calcium release CICR via couplons, clusters of ryanodine receptors RyRs. How such regeneration is terminated is uncertain. We performed numerical simulations of an idealized stochastic model of spark production, assuming a RyR gating scheme with only two states open and closed.
Local depletion of calcium in the SR was inevitable during a spark, and this could terminate sparks by interrupting CICR, with or without assumed modulation of RyR gating by SR lumenal calcium. Using a highly simplified, deterministic model of the dynamics of a couplon, we show that spark metastability depends on the kinetic relationship of RyR gating and junctional SR refilling rates.
The conditions for spark metastability resemble those produced by known mutations of RyR2 and CASQ2 that cause life-threatening triggered arrhythmias, and spark metastability may be mitigated by altering the kinetics of the RyR in a manner similar to the effects of drugs known to prevent those arrhythmias.
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